Renal Cell Carcinoma (Carbonic Anhydrase IX) Antibody, IgG2b, Clone: [CA9/3406], Mouse, Monoclonal

Product Overview

• Article Name: Renal Cell Carcinoma (Carbonic Anhydrase IX) Antibody, IgG2b, Clone: [CA9/3406], Mouse, Monoclonal
• Biozol Catalog Number: NBT-768-MSM6-P1
• Supplier Catalog Number: 768-MSM6-P1
• Alternative Catalog Number: NBT-768-MSM6-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: FC, IHC, WB
• Species Reactivity: Human
• Immunogen: Recombinant human CA9 protein fragment (around aa314-410) (exact sequence is proprietary)
• Alternative Names: CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, Carbonic anhydrase IX, G250, Membrane antigen MN,P54/58N, pMW1, RCC-associated antigen G250, Renal cell carcinoma-associated antigen G250

Product Description

Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200).In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowmans capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [CA9/3406]
• Molecular Weight: 55kDa
• Isotype: IgG2b
• NCBI: 768
• UniProt: Q16790
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Formalin-fixed, paraffin-embedded human kidney stained with CAIX-Monospe

Formalin-fixed, paraffin-embedded human kidney stained with CAIX-Monosp