Nucleolar complex-associated protein 4-like protein (NOC4L) Antibody, IgG1, Clone: [PCRP-NOC4L-1B2], Mouse, Monoclonal

Product Overview

• Article Name: Nucleolar complex-associated protein 4-like protein (NOC4L) Antibody, IgG1, Clone: [PCRP-NOC4L-1B2], Mouse, Monoclonal
• Biozol Catalog Number: NBT-79050-MSM1-P0
• Supplier Catalog Number: 79050-MSM1-P0
• Alternative Catalog Number: NBT-79050-MSM1-P0-20,NBT-79050-MSM1-P0-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: FC, IF
• Species Reactivity: Human
• Immunogen: Recombinant full-length human NOC4L protein
• Alternative Names: NOC4 protein homolog, NOC4-like protein, Nucleolar complex protein 4 homolog, Nucleolar complex-associated protein 4-like protein

Product Description

Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]

Product Properties

• Clonality: Monoclonal
• Clone Designation: [PCRP-NOC4L-1B2]
• Molecular Weight: 58.4kDa
• Isotype: IgG1
• NCBI: 79050
• UniProt: Q9BVI4
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Notes: Flow Cytometry (1-2ug/million cells), ,Immunofluorescence (1-2ug/ml), ,Optimal dilution for a specific application should be determined.

Images

SDS-PAGE Analysis of Purified NOC4L Mouse Monoclonal Antibody (PCRP-NOC4L-1B2). Confirmation of Integrity and Purity of Antibody.

Immunofluorescence Analysis of PFA-fixed HeLa cells. NOC4L Mouse Monoclonal Antibody (PCRP-NOC4L-1B2) followed by goat anti-mouse IgG-CF488 (blue), isotype control (red).

Immunofluorescence Analysis of PFA-fixed HeLa cells. NOC4L Mouse Monoclonal Antibody (PCRP-NOC4L-1B2) followed by goat anti-mouse IgG-CF488 (green), phalloidin (red).