Recombinant fragment (around aa1-200) of human IL18R1 protein (exact sequence is proprietary)
Alternative Names:
CD218 antigen-like family member A, CDw218a antigen, IL-18R1, IL-1Rrp, IL1 receptor-related protein, Il18ralpha,IL1R-rp, IL1RRP, Interleukin 18 receptor, alpha chain
Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-ve OO production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin s disease cell lines, and does not bind IL-1 or IL-1. The association of IL-18 to IL-18R leads to activation of NFve OOB. At present two subunits of IL-18R have been characterized: IL-18R and IL-18R. IL-18R has been described as the ligand-binding chain and IL-18R as the signal-transduction chain.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified IL18R1 Mouse Monoclonal Antibody (IL18R1/7593). Confirmation of Purity and Integrity of Antibody.
