BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1,14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Recombinant Monoclonal Antibody
Application Notes:
Flow Cytometry (1-2ug/million cells), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling
SDS-PAGE Analysis of Purified BCL10 Recombinant Mouse Monoclonal Antibody (rBL10/411). Confirmation of Purity and Integrity of Antibody.
Flow Cytometric Analysis of PFA-fixed K562 cells using BCL10 Recombinant Mouse Monoclonal Antibody (rBL10/411) followed by Goat anti-mouse IgG-CF488 (Blue), Isotype Control (Red),
Western Blot Analysis of Human Spleen, Human Stomach, HCT116, K-562 and Ramos lysates using BCL10 Recombinant Mouse Monoclonal Antibody (rBL10/411).
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