Recombinant CD2 / Lymphocyte Function Antigen 2 (LFA-2) Antibody, Clone: [LFA2/3417R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant CD2 / Lymphocyte Function Antigen 2 (LFA-2) Antibody, Clone: [LFA2/3417R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-914-RBM7-P1
• Supplier Catalog Number: 914-RBM7-P1
• Alternative Catalog Number: NBT-914-RBM7-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human
• Immunogen: Recombinant fragment corresponding to N-terminal of human CD2 protein (exact sequence is proprietary)
• Alternative Names: Erythrocyte receptor, LFA-2, LFA-3 receptor, Ly-37, Lymphocyte function antigen 2, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, T11

Product Description

CD2 is mainly present on the surface of mature T cells and NK cell membranes, while B cells are usually not expressed. It can be used to label the diagnosis and study of normal T cells and their associated tumors, such as pre-t cell lymphoma, marginal T cell lymphoma and anaplastic cell lymphoma. CD2 antibody is useful for identification of precursor and mature T-cell lymphomas. Aberrant loss of CD2 in T-cell lymphomas may help to distinguish them from reactive T-cell proliferations.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [LFA2/3417R]
• Molecular Weight: 39kDa
• NCBI: 914
• UniProt: P06729
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Formalin-fixed, paraffin-embedded human tonsil stained with CD2

Formalin-fixed, paraffin-embedded human tonsil stained with CD2 Recombinant Rabbit Monoclonal Antibody (LFA2/3417R). Inset: PBS instead of primary antibody, secondary only negative control.

Formalin-fixed, paraffin-embedded human tonsil stained with CD2 Recombinant Rabbit Monoclonal Antibody (LFA2/3417R) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.

Formalin-fixed, paraffin-embedded human lymph node stained with CD2 Recombinant Rabbit Monoclonal Antibody (LFA2/3417R). HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.

IHC analysis of formalin-fixed, paraffin-embedded human brain. Negative tissue control using LFA2/3417R at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.

SDS-PAGE Analysis Purified CD2 Recombinant Rabbit Monoclonal Antibody (LFA2/3417R). Confirmation of Purity and Integrity of Antibody.

Western blot analysis of Jurkat cell lysate using CD2 Recombinant Rabbit Monoclonal Antibody (LFA2/3417R).

Western Blot Analysis of Human Spleen tissue lysate using CD2 Recombinant Rabbit Monoclonal Antibody (LFA2/3417R).

Western Blot Analysis of Spleen tissue lysates of different species using CD2 Recombinant Rabbit Monoclonal Antibody (LFA2/3417R).