Recognizes a 67kDa transmembrane protein, which is identified as CD5 (HLDA I, WS Code T 29HLDA III, WS Code T 530). The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Application Notes:
Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Functional Studies (Order Ab without BSA & Azide), Immunoprecipitation (0.5-1ug/500ug protein lysate), Optimal dilution for a specific application should be determined.
FCM staining of human PBMCs using CD5 Monoclonal Antibody (CRIS-1).
FCM staining of human PBMCs using CD5 Monoclonal Antibody (CRIS-1).
SDS-PAGE Analysis of Purified CD5 Monoclonal Antibody (CRIS-1). Confirmation of Integrity and Purity of Antibody.
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