CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody, IgG3, Clone: [203.6], Mouse, Monoclonal

Product Overview

• Article Name: CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody, IgG3, Clone: [203.6], Mouse, Monoclonal
• Biozol Catalog Number: NBT-939-MSM1-P1
• Supplier Catalog Number: 939-MSM1-P1
• Alternative Catalog Number: NBT-939-MSM1-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: FC, IF
• Species Reactivity: Human
• Immunogen: Sezary cells
• Alternative Names: LPFS2, S152, T cell activation antigen S152, T-cell activation antigen CD27, T14, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7

Product Description

Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI, Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [203.6]
• Molecular Weight: 120kDa
• Isotype: IgG3
• NCBI: 939
• UniProt: P26842
• Form: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

SDS-PAGE Analysis of Purified CD27 Mouse Monoclonal Antibody (203.6). Confirmation of Integrity and Purity of Antibody