CD27 (also known as S152 or T14) is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell costimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.
200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified CD27 Recombinant Mouse Monoclonal Antibody (r137B4). Confirmation of Purity and Integrity of Antibody.
Western Blot analysis of Human Spleen and Ramos lysates using CD27 Recombinant Mouse Monoclonal Antibody (r137B4).
Western Blot Analysis of Human Spleen, Mouse Spleen, Rat Spleen, Hamster Spleen, Guinea pig Spleen and Rabbit Spleen tissue lysates using CD27 Recombinant Mouse Monoclonal Antibody (r137B4).
Formalin-fixed, paraffin-embedded human tonsil stained with CD27 Recombinant Mouse Monoclonal Antibody (r137B4). Inset: PBS instead of primary antibody, secondary only negative control.
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