CD36 (Platelet & Microvessel Marker) Antibody, IgG2a, Clone: [CD36/7218], Mouse, Monoclonal

Product Overview

• Article Name: CD36 (Platelet & Microvessel Marker) Antibody, IgG2a, Clone: [CD36/7218], Mouse, Monoclonal
• Biozol Catalog Number: NBT-948-MSM8-P0
• Supplier Catalog Number: 948-MSM8-P0
• Alternative Catalog Number: NBT-948-MSM8-P0-20,NBT-948-MSM8-P0-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human
• Immunogen: Recombinant full-length human CD36 protein
• Alternative Names: Adipocyte membrane protein, CHDS7, Collagen receptor, platelet, fatty acid translocase (FAT), Fatty acid transport protein, glycoprotein iiib (GP IIIb), PAS IV, PAS-4, pas4 protein, platelet collagen receptor, Platelet glycoprotein 4, scarb3, Scavenger receptor class B member 3, thrombospondin receptor

Product Description

Recognizes a protein of 80kDa-90kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [CD36/7218]
• Molecular Weight: 80-90kDa
• Isotype: IgG2a
• NCBI: 948
• UniProt: P16671
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Notes: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),Optimal dilutio

Images

Western Blot Analysis of human heart tissue lysate using CD36 Mouse Monoclonal Antibody (CD36/7218).

SDS-PAGE Analysis of Purified CD36 Mouse Monoclonal Antibody(CD36/7218). Confirmation of Purity and Integrity of Antibody

Formalin-fixed, paraffin-embedded human spleen stained with CD36 Mouse Monoclonal Antibody (CD36/7218) at 2ug/ml. Inset: PBS instead of primary antibody, secondary only negative control.