CD44v4/5 (Marker of Tumor Metastasis) Antibody, IgG1, Clone: [3D2], Mouse, Monoclonal

Catalog Number: NBT-960-MSM19-P0
Article Name: CD44v4/5 (Marker of Tumor Metastasis) Antibody, IgG1, Clone: [3D2], Mouse, Monoclonal
Biozol Catalog Number: NBT-960-MSM19-P0
Supplier Catalog Number: 960-MSM19-P0
Alternative Catalog Number: NBT-960-MSM19-P0-20,NBT-960-MSM19-P0-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: FC, IHC, WB
Species Reactivity: Human
Immunogen: Recombinant human full-length CD44v3-10 protein
Alternative Names: LHR, BA-1, chondroitin sulfate proteoglycan 8 (CSPG8), Epican, Extracellular Matrix Receptor III (ECM III), GP90 Lymphocyte Homing Adhesion Receptor, HCAM, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan Sulfate Proteoglycan, Hermes Antigen, HAS, HUTCH I, Hyaluronate Receptor, Indian blood group, Inlu Related p80 Glycoprotein, Ly 24, MDU2, MDU3, MIC4, MUTCH I, Phagocytic Glycoprotein 1 (PGP-1)
This antibody recognizes an epitope encoded by exon v9 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA.The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.
Clonality: Monoclonal
Clone Designation: [3D2]
Molecular Weight: 80-95kDa
Isotype: IgG1
NCBI: 960
UniProt: P16070
Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Application Notes: Flow Cytometry (1-2ug/million cells), Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95
SDS-PAGE Analysis of Purified CD44v4/5 Mouse Monoc
Formalin-fixed, paraffin-embedded human Cervix stained with CD44v4/5 Mouse Monoclonal Antibody (3D2).
Formalin-fixed, paraffin-embedded human Cervix stained with CD44v4/5 Mouse Monoclonal Antibody (3D2).
SDS-PAGE Analysis of Purified CD44v4/5 Mouse Monoclonal Antibody (3D2). Confirmation of Purity and Integrity of Antibody.