CD44v6 (Marker of Tumor Metastasis) Antibody, IgG2a, Clone: [CD44v6/1246], Mouse, Monoclonal

Product Overview

• Article Name: CD44v6 (Marker of Tumor Metastasis) Antibody, IgG2a, Clone: [CD44v6/1246], Mouse, Monoclonal
• Biozol Catalog Number: NBT-960-MSM7-P0
• Supplier Catalog Number: 960-MSM7-P0
• Alternative Catalog Number: NBT-960-MSM7-P0-20,NBT-960-MSM7-P0-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant fragment corresponding to the v6 domain of human CD44
• Alternative Names: LHR, BA-1, chondroitin sulfate proteoglycan 8 (CSPG8), Epican, Extracellular Matrix Receptor III (ECM III), GP90 Lymphocyte Homing Adhesion Receptor, HCAM, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan Sulfate Proteoglycan, Hermes Antigen, HAS, HUTCH I, Hyaluronate Receptor, Indian blood group, Inlu Related p80 Glycoprotein, Ly 24, MDU2, MDU3, MIC4, MUTCH I, Phagocytic Glycoprotein 1 (PGP-1)

Product Description

This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA.The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [CD44v6/1246]
• Molecular Weight: 80-95kDa
• Isotype: IgG2a
• NCBI: 960
• UniProt: P16070
• Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Notes: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes), Optimal dilution f

Images

SDS-PAGE Analysis of Purified

Formalin-fixed, paraffin-embedded human Cervical Carcinoma stained with CD44v6 Monoclonal Antibody (CD44v6/1246)

Formalin-fixed, paraffin-embedded human Tongue Carcinoma stained with CD44v6 Monoclonal Antibody (CD44v6/1246)

SDS-PAGE Analysis of Purified CD44v6 Monoclonal Antibody (CD44v6/1246). Confirmation of Purity and Integrity of Antibody.