A recombinant fragment (around aa 18-135) of human CD47 protein (exact sequence is proprietary)
Alternative Names:
Antigenic Surface Determinant Protein OA3, IAP, Integrin Associated Protein, Integrin Associated Signal Transducer, MER6, OA3, Protein MER6, Rh Related Antigen
This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis Purified CD47 Recombinant Rabbit Monoclonal Antibody (CD47/6364R). Confirmation of Integrity and Purity of Antibody.
Formalin-fixed, paraffin-embedded human prostate carcinoma stained with CD47 Recombinant Rabbit Monoclonal Antibody (CD47/6364R).
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