Recombinant CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker) Antibody, Clone: [CD70/12768R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker) Antibody, Clone: [CD70/12768R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-970-RBM22-P1
• Supplier Catalog Number: 970-RBM22-P1
• Alternative Catalog Number: NBT-970-RBM22-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant fragment corresponding to the C-terminus of human CD70 protein (exact sequence is proprietary)
• Alternative Names: CD27 ligand (CD27L), CD27LG, Ki24, Surface antigen CD70, Tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7)

Product Description

It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [CD70/12768R]
• Molecular Weight: 30kDa
• NCBI: 970
• UniProt: P32970
• Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

SDS-PAGE Analysis of Purified CD70 Recombinant Rabbit Monoclonal Antibody (CD70/12928R). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human renal cell carcinoma stained with CD70 Recombinant Rabbit Monoclonal Antibody (CD70/12768R). Inset: PBS instead of primary antibody, secondary only negative control.