Recombinant fragment of human CD79b protein (exact sequence is proprietary)
Alternative Names:
AGM6, B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, B29, B29/Ig-beta/CD79b, CD79b, Ig-beta, IGB, Immunoglobulin-associated B29 protein
CD79 (also designated Ig /Ig ) is a heterodimer composed of chains, designated CD79A or MB-1, and chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis Purified CD79b Mouse Monoclonal Antibody (CD79b/4960). Confirmation of Integrity and Purity of Antibody.
Formalin-fixed, paraffin-embedded human Tonsil stained with CD79b Mouse Monoclonal Antibody (CD79b/4960). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
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