Nidogen / Entactin Antibody, IgG2a, Clone: [ELM1], Rat, Monoclonal
Biozol Catalog Number:
NBT-MS18073-RTM1-P1ABX
Supplier Catalog Number:
MS18073-RTM1-P1ABX
Alternative Catalog Number:
NBT-MS18073-RTM1-P1ABX-100
Manufacturer:
NeoBiotechnologies
Host:
Rat
Category:
Antikörper
Application:
ELISA
Species Reactivity:
Guinea pig, Mouse
Immunogen:
Murine EHS laminin preparation
Alternative Names:
Nid1, Ent, Entactin 1, NID-1, Nidogen-1,
It reacts with the intact (150kDa) nidogen as well as its proteolytic fragments of 135kDa, 110kDa, 100kDa, and 80kDa. This MAb does not cross-react with other basement membrane components or fibronectin. Entactin/Nidogen is a ubiquitous multi-domain basement membrane protein. Basement membranes are the earliest extracellular matrices produced during embryogenesis. They are synthesized and incorporated into the supramolecular architecture of several components, including laminins, Collagen IV, Nidogen and proteoglycans. Nidogen/Entactin, a sulfated glycoprotein, acts as a link between the extracellular matrix molecules Laminin 1 and Collagen Type IV, and thereby participates in the assembly of basement membranes. Nidogen is synthesized and secreted in primary and established mesenchymal peritubular cells and myoepithelial cells, and it affects adhesion of peritubular cells in an autocrine manner. Nidogen is expressed during embryonic and fetal development exclusively in fully developed basement membranes of the ectoderm and is not expressed in the developing endodermal basement membrane or in membranes disrupted during mesoderm formation.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Application Notes:
ELISA (Use Ab at 2-4ug/ml for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.
SDS-PAGE Analysis of Purified Nidogen Mouse Monoclonal Antibody (ELM1). Confirmation of Purity and Integrity of Antibody.
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