Extract of a formalin-fixed, rejected-allograft of a human liver
Alternative Names:
Not Known
Hepatocyte Specific Antigen, also called Hepatocyte Paraffin 1 or HepPar1, localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCCs occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Clonality:
Monoclonal
Clone Designation:
[OCH1E5]
Molecular Weight:
Not Known
Isotype:
IgG1
NCBI:
Not Known
Form:
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Application Notes:
Immunofluorescence (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minut
Formalin-fixed, paraffin-embedded human Liver stained with Hepatocyte Specific Antigen Mouse Monoclonal Antibody (OCH1E5).
Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with Hepatocyte Specific Antigen Mouse Monoclonal Antibody (OCH1E5).
SDS-PAGE Analysis of Purified Hepatocyte Specific Antigen Mouse Monoclonal Antibody (OCH1E5). Confirmation of Purity and Integrity of Antibody.
* VAT and and shipping costs not included. Errors and price changes excepted
