Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8
Alternative Names:
HHV8, Human Herpes Virus 8, Human herpesvirus 8, Kaposis sarcoma associated herpes virus, KSHV
HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients, kaposis sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castlemans disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.
Clonality:
Monoclonal
Clone Designation:
[HHV8/3606]
Molecular Weight:
Not Known
Isotype:
IgG1
NCBI:
Not Applicable
Form:
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Recombinant Monoclonal Antibody
Application Notes:
ELISA (For coating use Ab at 1-5ug/ml, order Ab without BSA), Immunofluorescence (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM
SDS-PAGE Analysis of Purified HHV8 Recombinant Mouse Monoclonal Antibody (HHV8/3606). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human Kaposis sarcoma stained with HHV8 Recombinant Mouse Monoclonal Antibody (HHV8/3606).
* VAT and and shipping costs not included. Errors and price changes excepted
