Nuclei from pokeweed mitogen stimulated human peripheral blood lymphocytes
Alternative Names:
Myeloid specific protein, p183 DNA-binding cytoplasmic protein
Recognizes 183kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. This MAb reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.
Clonality:
Monoclonal
Clone Designation:
[BM-2]
Molecular Weight:
183kDa
Isotype:
IgG1
NCBI:
Not Known
Form:
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human Tonsil stained with Myeloid Specific Mouse Monoclonal Antibody (BM-2).
SDS-PAGE Analysis of Purified Myeloid Specific Mouse Monoclonal Antibody (BM-2). Confirmation of Purity and Integrity of Antibody.
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