Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody, IgG1, Clone: [AE-3], Mouse, Monoclonal
Biozol Catalog Number:
NBT-MSM5-257-P1
Supplier Catalog Number:
MSM5-257-P1
Alternative Catalog Number:
NBT-MSM5-257-P1-100
Manufacturer:
NeoBiotechnologies
Host:
Mouse
Category:
Antikörper
Application:
FC, IF, IHC, WB
Species Reactivity:
Bovine, Canine, Gallus, Human, Monkey, Mouse, Rabbit, Rat
Immunogen:
Human epidermal keratin
Alternative Names:
KRT2B, KRT2P, HUMCYT2A, Keratin, type II Cytoskeletal 2 oral, K76, Keratin 2p (K2P), Keratin-76, Cytokeratin-2P (CK-2P, Type-II Keratin Kb9
This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1), 64kDa (CK3), 59kDa (CK4), 58kDa (CK5), 56kDa (CK6), 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50, 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human skin stained with Cytokeratin, HMW Mouse Monoclonal Antibody (AE-3).
SDS-PAGE Analysis of Purified Cytokeratin, HMW Mouse Monoclonal Antibody (AE-3). Confirmation of Purity and Integrity of Antibody.
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