Cytokeratin, pan (Epithelial Marker) Antibody, Clone: [MonoPoly/7249R], Rabbit, Monoclonal
Biozol Catalog Number:
NBT-RBMP49-7249-P1ABX
Supplier Catalog Number:
RBMP49-7249-P1ABX
Alternative Catalog Number:
NBT-RBMP49-7249-P1ABX-100
Manufacturer:
NeoBiotechnologies
Host:
Rabbit
Category:
Antikörper
Application:
FC, IF, IHC, WB
Species Reactivity:
Human
Immunogen:
Recombinant fragments and/or synthetic peptides of human KRT76 and KRT77 proteins (exact sequences are proprietary)
Alternative Names:
K1B, KRT1B, Keratin, type II cytoskeletal 1b, K77, CK-1B, Keratin 1B, Keratin-77, Cytokeratin-1B, Type-II Keratin Kb39
MonoPoly antibodies are designed by pooling several monospecific, recombinant monoclonal antibodies against a target. MonoPoly antibodies are a kind of synthetic polyclonal antibodies that can be produced in unlimited quantity with a strict lot-to-lot consistency. These antibodies are highly specific with exquisite sensitivity and a single MonoPoly antibody can be used for a variety ofapplications.Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67kDa (CK1), 64kDa (CK3), 59kDa (CK4), 58kDa (CK5), 56kDa (CK6), 52kDa (CK8), 56.5kDa (CK10), 50kDa (CK14), 50kDa (CK15), 48kDa (CK16), 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.It may beuseful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas.
Clonality:
Monoclonal
Clone Designation:
[MonoPoly/7249R]
Molecular Weight:
40-67kDa
NCBI:
Multiple
Form:
200ug/ml of Ab purified by Protein A. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Recombinant Antibody
Application Notes:
Flow Cytometry (0.5-1ug/million cells), Immunofluorescence (1-2ug/ml), Western Blot (1-2ug/ml),,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1
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