EDG-6 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-6 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effect
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Source:
Rabbits were immunized with a synthetic peptide derived from the C-terminal of the EDG-6 receptor
Purity:
Ammonium Sulfate Precipitation
Form:
Unconjugated
Formula:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Application Notes:
Detects EDG6 receptors at concentration of 5-10 µg/ml by Western blot using a human EDG6 receptor transfected cell line. Detects an approximately 45 kDa band in Cos cells transfected with full length human EDG6. Due to low expression of EDG receptors, we recommend use of Pierce Femto Signal substrate for western blot development. Optimal concentration should be evaluated by serial dilutions.
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