The antibody to SRalpha was raised against a recombinant protein corresponding to amino acids 39-295 which includes part of the amino terminal SRbeta binding region and the hinge region between it and the carboxyl-terminal GTPase domain.
Conjugation:
Unconjugated
Alternative Names:
Signal Recognition Particle Receptor, alpha subunit
The receptor for Signal Recognition Particle (SRP) is the site on the endoplasmic reticulum that ribosomes translating secreted and integral membrane proteins are initially targeted to. Once the ribosome-SRP complex arrives at the SRP receptor the protei
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purity:
Ammonium Sulfate Precipitation
Formula:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Application Notes:
Detects SRalpha by Western blot analysis at 1 to 5 µg/ml. Also can be used to immunoprecipitate both subunits of SRP receptors under non-denaturing conditions. Optimal concentration should be evaluated by serial dilutions.
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