A portion of amino acids 451-481 from the mouse protein was used as the immunogen for this PARP3 antibody.
PARP3, poly(ADP-ribosyl)transferase 3, belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This protein is preferentially localized to the daughter centriole throughout the cell cycle.