MET Antibody (HGFR), Clone: [4AT44], Mouse, Monoclonal

Product Overview

• Article Name: MET Antibody (HGFR), Clone: [4AT44], Mouse, Monoclonal
• Biozol Catalog Number: NSJ-F40179-0.4ML
• Supplier Catalog Number: F40179-0.4ML
• Alternative Catalog Number: NSJ-F40179-0.4ML
• Manufacturer: NSJ Bioreagents
• Host: Mouse
• Category: Antikörper
• Application: ELISA, IF, IHC, WB
• Species Reactivity: Human, Mouse
• Immunogen: This MET antibody was produced from mice immunized with purified recombinant protein encoding the catalytic domain of human MET/HGFR.

Product Description

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Product Properties

• Clonality: Monoclonal
• Concentration: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Clone Designation: [4AT44]
• Isotype: Mouse IgG1
• UniProt: P08581
• Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Purity: Purified
• Form: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Target: MET
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: Western blot: 1:1000,Immunofluorescence: 1:100,IHC (Paraffin): 1:25-1:100
• Application Notes: Titration of the MET antibody (HGFR) may be required due to differences in protocols and secondary/substrate sensitivity.

Images

Immunohistochemical analysis of paraffin-embedded human liver using MET antibody at 1:25 dilution.

Fluorescent confocal image of