SUMO1 Antibody, Rabbit, Polyclonal
Catalog Number:
NSJ-F42001-0.4ML
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| Article Name: | SUMO1 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | NSJ-F42001-0.4ML |
| Supplier Catalog Number: | F42001-0.4ML |
| Alternative Catalog Number: | NSJ-F42001-0.4ML |
| Manufacturer: | NSJ Bioreagents |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, FACS, IF, IHC, WB |
| Species Reactivity: | Human |
| Immunogen: | A portion of amino acids 1-30 from the human protein was used as the immunogen for this SUMO1 antibody. |
| Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1. |
| Clonality: | Polyclonal |
| UniProt: | P63165 |
| Purity: | Purified |
| Form: | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Antibody Type: | Primary Antibody |
| Application Dilute: | Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50 |
| Application Notes: | Titration of the SUMO1 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
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