This FAP antibody was produced from rabbits immunized with the protein of human FAP.
Fibroblast activation protein is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.
The stated application concentrations are suggested starting amounts. Titration of the FAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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