A portion of amino acids 246-273 from the human protein (alpha) was used as the immunogen for this Estrogen Receptor antibody.
This gene encodes an Estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. ERs are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
Application Notes:
The stated application concentrations are suggested starting amounts. Titration of the Estrogen Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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