MGMT Antibody, Rabbit, Polyclonal

Product Overview

• Article Name: MGMT Antibody, Rabbit, Polyclonal
• Biozol Catalog Number: NSJ-F43302-0.4ML
• Supplier Catalog Number: F43302-0.4ML
• Alternative Catalog Number: NSJ-F43302-0.4ML
• Manufacturer: NSJ Bioreagents
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, WB
• Species Reactivity: Human
• Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this MGMT antibody.

Product Description

MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Product Properties

• Clonality: Polyclonal
• UniProt: P16455
• Purity: Antigen affinity
• Form: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: Western blot: 1:1000,Immunofluorescence: 1:10-1:50
• Application Notes: Titration of the MGMT antibody may be required due to differences in protocols and secondary/substrate sensitivity.