A portion of amino acids 298-328 from the human protein was used as the immunogen for this GATA4 antibody.
GATA4 is a transcriptional activator that binds to the consensus sequence 5-AGATAG-3 and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development. [UniProt]