This mouse Wdr5 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the region of mouse Wdr5.
Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at Lys-4. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity).
