Human recombinant protein corresponding to amino acids 782-1038 was used as the immunogen for this AIP1 antibody.
ASK-interacting protein 1 functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control, reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. [UniProt]
