Thrombomodulin Antibody (C-Terminal Region), Rabbit, Polyclonal

Catalog Number: NSJ-F54086-0.2ML
Article Name: Thrombomodulin Antibody (C-Terminal Region), Rabbit, Polyclonal
Biozol Catalog Number: NSJ-F54086-0.2ML
Supplier Catalog Number: F54086-0.2ML
Alternative Catalog Number: NSJ-F54086-0.2ML
Manufacturer: NSJ Bioreagents
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human
Immunogen: A portion of amino acids 537-571 from human THBD was used as the immunogen for the Thrombomodulin antibody.
Thrombomodulin/THBD/TM/CD141 is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [UniProt]
Clonality: Polyclonal
UniProt: P07204
Purity: Antigen affinity
Form: In 1X PBS, pH 7.4, with 0.09% sodium azide
Antibody Type: Primary Antibody
Application Dilute: Western blot: 1:2000
Application Notes: The stated application concentrations are suggested starting points. Titration of the Thrombomodulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.