A portion of amino acids 820-854 from human THBS1 was used as the immunogen for the Thrombospondin 1 antibody.
Thrombospondin is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity). [UniProt]
The stated application concentrations are suggested starting points. Titration of the Thrombospondin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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