A portion of amino acids 123--157 from human VAV2 was used as the immunogen for the VAV2 antibody.
Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). [UniProt]
The stated application concentrations are suggested starting points. Titration of the VAV2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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