Recombinant human RGMB was used as the immunogen for the RGMB antibody.
Repulsive Guidance Molecule B is a member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth. [UniProt]
The stated application concentrations are suggested starting points. Titration of the RGMB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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