Glutaminase Antibody / GLS, Rabbit, Polyclonal

Product Overview

• Article Name: Glutaminase Antibody / GLS, Rabbit, Polyclonal
• Biozol Catalog Number: NSJ-F54260-0.2ML
• Supplier Catalog Number: F54260-0.2ML
• Alternative Catalog Number: NSJ-F54260-0.2ML
• Manufacturer: NSJ Bioreagents
• Host: Rabbit
• Category: Antikörper
• Application: FACS, IF, IHC-P, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A portion of amino acids 516-545 from the human protein were used as the immunogen for the Glutaminase antibody.

Product Description

Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.

Product Properties

• Clonality: Polyclonal
• UniProt: O94925
• Purity: Antigen affinity purified
• Form: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: Western blot: 1:1000-1:2000,Immunofluorescence: 1:25,Immunohistochemistry (FFPE): 1:100-1:200,Flow cytometry: 1:25 (per 1x10e6 cells)
• Application Notes: The stated application concentrations are suggested starting points. Titration of the Glutaminase antibody may be required due to differences in protocols and secondary/substrate sensitivity.