Natriuretic peptide receptor C Antibody / NPRC, Mouse, Polyclonal

Catalog Number: NSJ-F55068-0.05ML
Article Name: Natriuretic peptide receptor C Antibody / NPRC, Mouse, Polyclonal
Biozol Catalog Number: NSJ-F55068-0.05ML
Supplier Catalog Number: F55068-0.05ML
Alternative Catalog Number: NSJ-F55068-0.05ML
Manufacturer: NSJ Bioreagents
Host: Mouse
Category: Antikörper
Application: IF, IHC-P, WB
Species Reactivity: Human
Immunogen: A portion of amino acids 67-97 from the human protein was used as the immunogen for the Natriuretic peptide receptor C antibody.
Natriuretic peptide receptor C / NPRC is a receptor protein found in various tissues, including the heart, kidney, and blood vessels. Its main function is to bind to natriuretic peptides, which are hormones that help regulate blood pressure and fluid balance. When natriuretic peptides bind to Natriuretic peptide receptor C, they are degraded and their effects are blocked, leading to an increase in blood pressure. Natriuretic peptide receptor C also plays a role in the development of heart failure. Research has shown that increased levels of NPRC in the body can lead to impaired responses to natriuretic peptides, which in turn can contribute to the progression of heart failure. In addition to its role in cardiovascular health, NPRC has also been implicated in other diseases, such as obesity and diabetes. Studies have shown that NPRC levels are elevated in patients with these conditions, suggesting a potential link between Natriuretic peptide receptor C and metabolic disorders.
Clonality: Polyclonal
UniProt: P17342
Form: In 1X PBS, pH 7.4, with 0.09% sodium azide
Antibody Type: Primary Antibody
Application Dilute: Western blot: 1:500-1:1000,Immunohistochemistry (FFPE): 1:10-1:50,Immunofluorescence: 1:100-1:200
Application Notes: Titration of the Natriuretic peptide receptor C antibody may be required due to differences in protocols and secondary/substrate sensitivity.