An E.coli-derived zebrafish recombinant protein (amino acids S2-E32) was used as the immunogen for the Zebrafish Srsf1 antibody. This antibody will detect the a and b isoforms.
Predicted to enable mRNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be active in nuclear speck. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with dysmorphic facies and behavioral abnormalities. Orthologous to human SRSF1 (serine and arginine rich splicing factor 1).
