An E.coli-derived zebrafish Sumo recombinant protein (amino acids Q25-T72) was used as the immunogen for the Zebrafish Sumo antibody. This antibody will detect isoforms 2, 3, 3b and 3l.
Predicted to enable protein tag activity and ubiquitin-like protein ligase binding activity. Acts upstream of or within chordate embryonic development and definitive hemopoiesis. Predicted to be active in nucleus. Is expressed in brain, cranial neural crest cell, digestive system, eye, and pectoral fin bud. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus 5. Orthologous to several human genes including SUMO2 (small ubiquitin like modifier 2).