Zebrafish Clpx Antibody / Isoforms a & b, Rabbit, Polyclonal
Biozol Catalog Number:
NSJ-RZ1040
Supplier Catalog Number:
RZ1040
Alternative Catalog Number:
NSJ-RZ1040
Manufacturer:
NSJ Bioreagents
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Zebrafish
Immunogen:
An E.coli-derived zebrafish Clpxa/b recombinant protein (amino acids A327-L564) was used as the immunogen for the Zebrafish Clpx antibody. This antibody will detect the a and b isoforms.
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial is an enzyme that in humans is encoded by the CLPX gene. This protein is a member of the family of AAA Proteins (AAA+ ATPase) and is to form the protein complex of Clp protease. The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
