MAP2 Antibody / Microtubule-associated protein 2, Clone: [MAP2/7673], Mouse, Monoclonal
Biozol Catalog Number:
NSJ-V4938SAF-100UG
Supplier Catalog Number:
V4938SAF-100UG
Alternative Catalog Number:
NSJ-V4938SAF-100UG
Manufacturer:
NSJ Bioreagents
Host:
Mouse
Category:
Antikörper
Application:
IHC-P
Species Reactivity:
Human
Immunogen:
A recombinant partial protein sequence (within amino acids 1500-1700) from the human protein was used as the immunogen for the MAP2 antibody.
Microtubules, the primary component of the cytoskeletal network, interact with proteins called microtubule-associated proteins (MAPs). The microtubule-associated proteins can be divided into two groups, structural and dynamic. The structural microtubule-associated proteins, MAP-1A, MAP-1B, MAP-2A, MAP-2B and MAP-2C, stimulate tubulin assembly, enhance microtubule stability and influence the spatial distribution of microtubules within cells. Both MAP-1 and, to a greater extent, MAP-2 have been implicated as agents of microtubule depolymerization by suppressing the dynamic instability of the microtubules. The suppression of microtubule dynamic instability by the MAP proteins is thought to be associated with phosphorylation of the MAPs.
