IL-1B activated human vascular endothelial cells expressing ICAM-1/CD54 protein were used as the immunogen for the recombinant CD54 antibody.
Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1), also called CD54. It has 7 potential N-linked glycosylation sites. ICAM-1/CD54 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes.
