CD50 Antibody / ICAM-3, Clone: [CG106], Mouse, Monoclonal

Product Overview

• Article Name: CD50 Antibody / ICAM-3, Clone: [CG106], Mouse, Monoclonal
• Biozol Catalog Number: NSJ-V7853SAF-100UG
• Supplier Catalog Number: V7853SAF-100UG
• Alternative Catalog Number: NSJ-V7853SAF-100UG
• Manufacturer: NSJ Bioreagents
• Host: Mouse
• Category: Antikörper
• Application: Blocking, FACS, IF
• Species Reactivity: Human
• Immunogen: Stimulated human leukocytes were used as the immunogen for the CD50 antibody.

Product Description

Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.

Product Properties

• Clonality: Monoclonal
• Concentration: 1 mg/ml in 1X PBS, BSA free, sodium azide free
• Clone Designation: [CG106]
• Isotype: Mouse IgG2a, kappa
• UniProt: P32942
• Buffer: 1 mg/ml in 1X PBS, BSA free, sodium azide free
• Purity: Protein G affinity chromatography
• Form: 1 mg/ml in 1X PBS, BSA free, sodium azide free
• Target: ICAM-3
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: Blocks binding of CD11a/LFA-1 to CD50/ICAM-3 (order BSA/azide-free format),Flow cytometry: 1-2ug/10 6 cells in 0.1ml,Immunofluorescence: 1-2ug/ml
• Application Notes: Optimal dilution of the CD50 antibody should be determined by the researcher.

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