Recombinant full-length human RBMS2 protein was used as the immunogen for the RBMS2 antibody.
RBMS2 is a member of a small family of proteins that bind single stranded DNA or RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, and are required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. RBMS2 (RNA-binding motif, single-stranded-interacting protein 2) is a 407 amino acid protein that contains 2 RRM (RNA recognition motif) domains and localizes to nucleus. It has been suggested that RBMS2 suppresses Cdc2 kinase and Cdc13 cyclin mutants through the induction of translation of Cdc2. The RBMS2 gene is conserved in chimpanzee, canine, bovine, mouse, rat and zebrafish, and maps to human chromosome 12q13.3.
ELISA (For coating, order BSA-free format),Immunoprecipitation: 1-2ug per 100-500ug of total protein (1ml of cell lysate),Flow cytometry: 1-2ug/million cells
Application Notes:
Optimal dilution of the RBMS2 antibody should be determined by the researcher.
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