EGF Receptor / EGFR Antibody (C-terminal region), Clone: [EGFR/4575], Mouse, Monoclonal

Product Overview

• Article Name: EGF Receptor / EGFR Antibody (C-terminal region), Clone: [EGFR/4575], Mouse, Monoclonal
• Biozol Catalog Number: NSJ-V9263-20UG
• Supplier Catalog Number: V9263-20UG
• Alternative Catalog Number: NSJ-V9263-20UG
• Manufacturer: NSJ Bioreagents
• Host: Mouse
• Category: Antikörper
• Application: IHC-P, WB
• Species Reactivity: Human
• Immunogen: A portion of amino acids 1163-1191 from the C-terminal region of human EGFR was used as the immunogen for the EGF Receptor antibody.

Product Description

This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [EGFR/4575]
• UniProt: P00533
• Purity: Protein A/G affinity
• Form: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: Western blot: 2-4ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
• Application Notes: Optimal dilution of the EGF Receptor antibody should be determined by the researcher.