Non-viable cell pellet was generated from cell line WM1862. WM1862 is a non-tumorigenic (RGP) primary human melanoma cell line without metastatic capability. This cell line displays pigmented, mesenchymal and spherical morphology. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. These cells expresses wild type N-RAS, c-KIT, and CDK4. WM1862 cells produce xenograft tumors when injected into immunocompromised mice.
Concentration:
5.0 million cells (Count By Hemocytometer)
Buffer:
None
Source:
Human
Form:
Frozen Cell Pellet
Application Notes:
Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation.
Human melanoma tumor cell pellets for assessment of proteins and their phosphorylation status
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