WM3246 is a metastatic human melanoma cell line that was established from an adrenal gland metastatic site of a female patient. This cell line expresses mutated PTEN gene and is wild type for BRAF, N-RAS, c-KIT and CDK4. WM3246 cells produce xenograft tumors when injected into immunocompromised mice.
Concentration:
1.0 million cells/mL (Count By Hemocytometer)
Buffer:
None
Source:
Human
Form:
Frozen Cell Suspension
Application Notes:
The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways.
Human melanoma tumor cells with known gene mutations, disease stage, STR, and RPPA profiling
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