WM3912 Non-Viable Cell Pellet

Catalog Number: ROC-WM3912-03-0005
Article Name: WM3912 Non-Viable Cell Pellet
Biozol Catalog Number: ROC-WM3912-03-0005
Supplier Catalog Number: WM3912-03-0005
Alternative Catalog Number: ROC-WM3912-03-0005
Manufacturer: Rockland Immunochemicals
Category: Zellen/Zellkultur
Conjugation: Unconjugated
Alternative Names: Melanoma, patient derived tumor, tumor models, skin cancer, xenograft
Non-viable cell pellet was generated from cell line WM3912. WM3912 is a metastatic human melanoma cell line established from a neck metastatic site of a patient. This cell line thaws poorly and contains lots of spontaneous senescent cells. This cell line features the N581Y mutation at codon 581 in the BRAF gene. The N581Y mutation results in an amino acid substitution at position 581 in the BRAF, from an asparagine (N) to a tyrosine (Y). This cell line also expresses L213F mutation in CDK4 gene which results in an amino acid substitution at codon 213 in the CDK4 from leucine (L) to phenylalanine (F). WM3912 cells produce xenograft tumors when injected into immunocompromised mice.
Concentration: 5.0 million cells (Count By Hemocytometer)
Buffer: None
Source: Human
Form: Frozen Cell Pellet
Application Notes: Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation.
Human melanoma tumor cell pellets for assessment of proteins and their phosphorylation status