SARS-CoV-2 S1RBD/ACE2 Binding Assay kit
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|Article Name:||SARS-CoV-2 S1RBD/ACE2 Binding Assay kit|
|Biozol Catalog Number:||TBS-41A249R|
|Supplier Catalog Number:||41A249R|
|Alternative Catalog Number:||TBS-41A249R|
SARS-COV2 virus enters human epithelial cells by the interaction between the receptorbinding domain of spike protein (S1RBD) on the surface of the viral particle and the ACE2 receptor on the surface of human cells. The S1RBD-ACE2 interaction is the crucial step of COVID-19 infection, and is therefore the principal target for development of vaccines and drugs against COVID-19. SARS-COV2 S1RBD-ACE2 Binding Assay can characterize the binding affinity of S1RBD-ACE2 receptor complex in the presence of potential inhibitors or neutralizing antibodies in a simple and sensitive manner.
This assay can be used for:
1. Measurement of circulating neutralizing antibody level in COVID-19 patients
2. Evaluation of dynamic changes in circulating neutralizing antibody level after vaccination
3. High throughput screening and validation of therapeutic compounds/antibodies targeting the S1RBD-ACE2 complex.