Indomethacin is an orally active nonsteroidal anti-inflammatory drug (NSAID) that non-selectively inhibits cyclooxygenase enzymes COX-1 and COX-2, with IC50 values of 18 nM and 26 nM, respectively. It exhibits good blood-brain barrier permeability and shows significant anti-inflammatory, anti-tumor, and anti-infective activities. Indomethacin is widely used in research related to cancer, inflammation, and viral infections, and is also commonly used to induce gastric ulcer models in animals.
Molecular Weight:
357.79
Purity:
0.9984
CAS Number:
[53-86-1]
Formula:
C19H16ClNO4
Target:
Phospholipase|||COX|||PDE|||Autophagy
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